Intended for Canadian Healthcare Professionals Only
Continuous, Active
Micro-Debridement

Micro-debridement with Collagenase SANTYL® Ointment selectively targets the collagen strands1 that hold microscopic cellular debris in place, helping break the cycle of inflammation.

Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone.
Use of Collagenase SANTYL® Ointment should be terminated when debridement is complete and granulation tissue is well established.
See complete prescribing information for more details.

Reference: 1. Mandl I. Collagenases and elastases, In: Nord FF, ed. Advances in Enzymology. New York, NY: Interscience Publishers, Inc.; 1961: 163-264.
Micro-debridement with Collagenase SANTYL
The Continuous,
Active Micro-Debrider

Collagenase SANTYL® Ointment is active enzymatic therapy1 that continuously removes necrotic tissue from wounds at the microscopic level.

Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone.
Use of Collagenase SANTYL® Ointment should be terminated when debridement is complete and granulation tissue is well established.
See complete prescribing information for more details.

Reference: 1. Mandl I. Collagenases and elastases, In: Nord FF, ed. Advances in Enzymology. New York, NY: Interscience Publishers, Inc.; 1961: 163-264.
Collagenase SANTYL Ointment
Mechanism of Action

Collagenase SANTYL® Ointment selectively cleaves the collagen bonds1 that hold necrotic debris to the wound bed.

Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone.
Use of Collagenase SANTYL® Ointment should be terminated when debridement is complete and granulation tissue is well established.
See complete prescribing information for more details.

Reference: 1. Mandl I. Collagenases and elastases, In: Nord FF, ed. Advances in Enzymology. New York, NY: Interscience Publishers, Inc.; 1961: 163-264.
Application Video
Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone.
Use of Collagenase SANTYL® Ointment should be terminated when debridement is complete and granulation tissue is well established.
See complete prescribing information for more details.

Reference: 1. Mandl I. Collagenases and elastases, In: Nord FF, ed. Advances in Enzymology. New York, NY: Interscience Publishers, Inc.; 1961: 163-264.
SANTYL® is a registered trademark of Healthpoint Biotherapeutics. Healthpoint Biotherapeutics and design is a registered trademark of Healthpoint Biotherapeutics.
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The information on this site is intended for customers, patients, and healthcare professionals in Canada only. All information, including the Prescribing Information for Collagenase SANTYL® Ointment, abides by the laws, regulatory requirements, and medical practices for Canada only and may not be appropriate for use outside of Canada.